Main Street Chillicothe


Displaying 26 Events:
Mommy and Me Tea Party
Apr 04, 2025
2:00 PM CDT
1725 Locust St
Chillicothe, MO 64601-2524
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Chillicothe Chamber - Spring-A-Palooza
Apr 05, 2025
10:00 AM CDT
1725 Locust St
Chillicothe, MO 64601
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Chillicothe Theatre Co Presents Marvelous Wonderettes.
Apr 06, 2025
7:00 PM CDT
401 Harvester Rd
Chillicothe, MO 64601
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Dungeons & Dragons for Adults
Apr 09, 2025
5:00 PM CDT
450 Locust St
Chillicothe, MO 64601
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YMCA Annual Easter Egg Hunt
Apr 12, 2025
10:00 AM CDT
1503 Walnut St
Chillicothe, MO 64601-2524
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Martin House Gifts - 15 Year Anniversary
Apr 12, 2025
10:00 AM CDT
504 Washington St
Chillicothe, MO 64601
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Chillicothe Downtown Cleanup
Apr 17, 2025
1:30 PM CDT
514 Washington Street
Chillicothe, MO 64601-2524
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Styled by Sarah - Salon Pop Up Party
Apr 19, 2025
2:00 PM CDT
610 Jackson St
Chillicothe, MO 64601
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Spread the Flavor: Herbed Butter
Apr 22, 2025
6:00 PM CDT
450 Locust St
Chillicothe, MO 64601
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Chillicothe Chamber & GRTS - Career Fair
Apr 24, 2025
9:00 AM CDT
10780 Liv 235
Chillicothe, MO 64601-2524
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Chillicothe High School Class of 2025 Graduation
May 11, 2025
3:00 PM CDT
2801 Hornet Road
Chillicothe, MO 64601-2524
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Toast to Home
Jun 06, 2025
5:00 PM CDT
707 Webster Street
Chillicothe, MO 64601
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Sliced Bread Day Kickoff
Jun 06, 2025
7:00 PM CDT
707 Webster Street
Chillicothe, MO 64601
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10th Annual "Battle at the Grand" Bulls and Barrels
Jun 06, 2025
7:30 PM CDT
10780 Liv 235
Chillicothe, MO 64601-2524
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Members Only Playing at Blackwater Restaurant and Lounge
Jun 21, 2025
5:00 PM CDT
612 First St
Chillicothe, MO 64601
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Main Street Chillicothe is a community-driven organization focused on revitalizing and preserving the historic downtown district. Through architectural preservation, economic development, and cultural promotion, it works to create a vibrant, attractive downtown. By supporting small businesses, fostering community engagement, and celebrating the city's rich history, Main Street Chillicothe ensures downtown remains a thriving hub of activity and growth. This place matters.

Brick by brick, hand in hand, and friend to friend. Help us continue our mission by donating today.

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shop with us

A day downtown starts with exploring our variety of retail stores, services, galleries, and more. Spend the day with friends strolling and shopping.

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yummy eats & drinks

Of course, with all that shopping you are going to get hungry and thirsty. Luckily for you, downtown has many delicious choices for all ages.

tag us w/ #dtchilliyums

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news & announcements

Dive into inspiring community updates, business spotlights, preservation projects, and more.

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this place matters

As a Missouri Main Street Accredited program, MAIN STREET CHILLICOTHE is a recognized, leading program among the state network of more than 50 districts and communities that share both a commitment to creating high-quality places and building stronger communities through preservation-based economic development.


As a Main Street America Accredited Program, Chillicothe Main Street, Inc. is a recognized leading program among the national network of more than 1,200 neighborhoods and communities who share both a commitment to creating high-quality places and to building stronger communities through preservation-based economic development. All Main Street America Accredited Programs meet a set of National Accreditation Standard of Performance as outlined by the National Main Street Center.