• 514 Washington Street Chillicothe, MO 64601-2524

  • 660-646-4071

    • Main Street Chillicothe

    Community News & Announcements 


    Ready, Set, PAINT!Get ready to paint the town with the Main-iacs on Main! We’re excited to announce a vibrant community project where our incredible 2024-...
    Chillicothe Cruise NightDowntown Chillicothe came alive with the sight of vintage automobiles, muscle cars, and custom rides meticulously restored and proudly d...
    Painting The Town With Toasty - A Colorful Adventure!The inner artists were unleashed as Main Street Chillicothe's spirited student volunteer group, the Main-iacs, proudly presented their l...
    Extra Extra Read All About ItOur community is a fantastic place to live because of the amazing people who make it so. They understand that it takes continuous effort...
    A.C.T.S with Lifepoint Church and Main Street ChillicotheOur beautiful downtown continues to thrive as a clean and welcoming spot for all community members and visitors. This success is largely...
    Sliced Bread Day CelebrationIt's that time of year again to celebrate Chillicothe’s claim to fame, sliced bread! Baker Frank Bench and inventor Otto Rohwedder made ...
    Timeless Treasures: Mural and Building Heritage TourOur downtown historic buildings and murals are a significant focal point in Chillicothe. The murals and buildings are captivating to vis...
    Summer 2024 Flower Pot ProgramHave you noticed the new pops of color downtown? If not, this is your invitation to take a stroll downtown Chillicothe and check out the...
    Main Street Now Conference From May 5th through May 8th, Main Street Chillicothe attended the National Main Street Now conference in Birmingham, Alabama. This year...
    Downtown Clean Up DayWith spring bringing new flowers and warmer weather, it was long overdue to shake off those winter blues. It was time for the always fun...
    Winter Décor Clean-Up DowntownAfter a spectacular Christmas display of the downtown planters, the Main Street Chillicothe volunteer decorations crew, “The Main Makers...
    Valentine Sweet StrollMain Street Chillicothe hosted its first Valentine's Sweet Stroll downtown on February 8th, 2024. The Sweet Stroll allowed attendees to ...